Postdoctoral Research on Genome-Wide tRNA Epigenetic Biology

2021年01月26日

米国Thomas Jefferson大学のYa-Ming Hou教授がポスドクを募集しています。RNA研究に興味と経験のある方なら誰でも応募してほしいということです。Hou博士は明るく温かいお人柄で、日本人のポスドクも何人もいたことがあるので、働きやすいと思います。Thomas Jefferson 大学は、フィラデルフィアの中心部(自由の鐘のすぐそば)にあり、住むのには安全で便利な場所です。より詳しく聞きたい方は、直接Hou教授にご連絡されるか(ya-ming.hou[at]jefferson.edu)、私(東京都立大学理学部生命科学科准教授 安藤香奈絵(k_ando[at]tmu.ac.jp)まで。

A postdoctoral position is available with Professor Ya-Ming Hou at Thomas Jefferson University, Philadelphia, USA. We explore tRNA epigenetic changes and how these changes control gene expression at the codon level and in response to cellular stress at the new frontier of molecular biology and the central dogma. We use a synthetic biology approach with CRISPR-edited genomes and CRISPRi approaches to determine how changes in tRNA epigenetic biology impact cell fitness in human health and disease. We provide an intellectually stimulating environment and encourage global networking.

Current projects on tRNA epigenetic biology focus on:

  • response to environmental stress
  • discovery of new bacterial physiology and antibiotic therapeutics
  • neurodegenerative diseases.

For more information, please see the following publications and our website:

Nat Communications (2021). https://rdcu.be/cdrb8
Cell Chem Biol (2020). PMID: 32553119
ACS Catal (2020). PMID: 32904895 (Featured as the cover)
Ann Neurol (2020). PMID: 32715519
Cell Systems (2019). PMID: 30981730 (Featured in Faculty 1000 Prime)
PNAS (2016). PMID: 27849575 (Featured in PNAS commentary)
Nat Struct Mol Biol (2016). PMID: 27571175. (Featured in Science)
Nature Communications (2015). PMID: 26009254
Chem and Biol (Cell Press) (2014). PMID: 25219964
Nature (2014). PMID: 24919148 (Featured in Nature News and Views)
Nat. Communications (2011). PMID: 21629262

https://houlaboratory.com/research

https://www.jefferson.edu/university/research/researcher/researcher-faculty/hou-laboratory.html

Candidates with a recent Ph.D. and a passion for basic research are encouraged to apply. Experience in RNA-seq, high-throughput data analysis, fluorescence microscopy, cell culture, molecular biology, enzymology, nucleic acids research, and protein biotechnology is preferred.

Please send a cover letter, CV, and contact information of three references to:

Ya-Ming Hou
Professor of Biochemistry and Mol Biology
Thomas Jefferson University
233 S. 10th Street, BLSB 220
Philadelphia, PA 19107, USA
T: 215-503-4480
Email: このメールアドレスはスパムボットから保護されています。閲覧するにはJavaScriptを有効にする必要があります。

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