Seeking a Research Scientist, Postdoctoral Researcher or Research Associate

2019年01月07日
Parrishゲノム免疫生物学理研白眉研究チームでは研究員を募集しています。

Seeking a Research Scientist, Postdoctoral Researcher or Research Associate at Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan (Team Leader: Nicholas Parrish M.D., Ph.D.)

Research Field

The primary objective of this research team is to investigate the potential immunological functions of endogenous viral sequences found in mammalian genomes. Some of these sequences have been observed to produce small RNAs that are antisense relative to the viral transcript from which they were derived (Parrish et al., RNA 2015). We are testing the hypothesis that such small RNAs are involved in antiviral immunity via RNA interference. This is interdisciplinary research integrating virology, immunology, genomics, epigenetics, RNA biology, evolutionary biology, and developmental biology. In the broad sense, we are studying cellular and organismal genomic plasticity in response to environmental stimuli (Sudmant, Parrish et al., Nature. 2015; Parrish et al., Current Opinion in Microbiology. 2016), in particular exogenous nucleic acid information (Parrish et al., Cell. 2018), and are open to hosting postdoctoral fellows with diverse research interests compatible with these topics.

Description

The primary project investigates the role of endogenous viral sequences in viral infection. The researcher will assist with generation, maintenance, infection, and postinfection assessment of genetically modified mice. The successful applicant will take advantage of the existing strengths of the Center for Integrative Medical Sciences’ immunology (Divisions of Human Immunology, Cancer Immunology, and Disease Systems Biology) and genomics (Division of Genomic Medicine) programs via active collaboration.

For more information, please email
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