The fellowship is placed at the Department of Medical Biosciences, which has approximately 100 employees and carries out high quality research and education. This position is also connected to the Wallenberg Centre for Molecular Medicine (WCMM) at Umeå University. WCMM in Umeå is part of a national plan for Sweden to regain its leading position in medical research (wcmm.umu.se). The centre is supported by the Knut and Alice Wallenberg Foundation, together with Umeå University, Västerbotten County Council, the Kempe Foundation and the Cancer Research Foundation in Northern Sweden.
The project will be conducted under the supervision of Dr. Francesca Aguilo. The research group investigates how changes in RNA modification contribute to breast cancer progression as well as drug resistance. The successful applicant will combine cellular biology with state-of-the-art molecular biology approaches, including ChIP-seq, RNA-seq, ATAC-seq, MeRiP-seq, CLIP-seq and other large-scale epigenomic and epitranscriptomic analyses, including single-cell RNA-seq. In addition, 2D and 3D cell culture models, patient samples as well as mouse transgenic models will be used to study the central RNA-based regulatory circuitry in breast tumorigenesis.
Qualification requirements and other desirable requirements
To be eligible for the fellowship, applicants must hold a PhD degree.
We are looking for a highly talented and motivated candidate with a strong background in molecular biology and expertise in CRISPR gene editing. Experience of working with breast cancer models is highly desirable. Proficiency in spoken and written English is essential. A strong publication record with at least one first-author research paper publication in a peer-reviewed journal is also required. The applicant must be able to work well both independently and as part of a team. Focus will be given to the candidate’s potential to work collaboratively within an interdisciplinary team.
The application should include the following:
• A cover letter (max two A4 pages) with a summary of research interests, career aims and why you are interested in the fellowship.
• Curriculum vitae (CV) and list of publications.
• Copies of relevant degree certificates and PhD thesis.
• Contact information (name, address, telephone and e-mail) for three referees.
See also the Nature jobs link.
Selected relevant publications:
Aguilo et al. Cell Stem Cell, 2015
Aguilo et al. Cell Reports, 2016
Aguilo et al. Current Opinion in Genetic & Develop, 2017