An exciting postdoctoral fellow position is available in the lab of Dr. Jacob Schwartz at the University of Arizona in Tucson, AZ, to study the role of RNA binding proteins in regulating transcription and DNA damage response.

Specific projects include the role of RNA binding proteins in Lou Gehrig’s disease, Ewing sarcoma, and the role of noncoding RNAs in regulating transcription. Candidates with a strong background in molecular biology, biochemistry, or computational biology are encouraged to apply. The lab’s research focus ranges from protein purification, cell culture, primary neuronal cell culture, and whole mouse studies. Techniques include mass spectrometry, protein/RNA structure functional studies, immunofluorescence and microscopy, and next-generation sequencing.

To apply please send a CV and letter of interest with the contact information for your references to このメールアドレスはスパムボットから保護されています。閲覧するにはJavaScriptを有効にする必要があります。.

Relevant Publications:
1. Schwartz JC, Cech TR, Parker RR, “Biochemical properties and biological functions of FET proteins”, Annu. Rev. Biochem. 2015; 84 (Epub ahead of print)
2. Schwartz JC, Podell ER, Han SSW, Berry JD, Eggan KC, Cech TR, “FUS is sequestered in nuclear aggregates in ALS patient fibroblasts” Mol Biol Cell, 2014; 25(17):2571-8. (PMID: 25009283)
3. Schwartz JC, Wang X, Podell ER, Cech TR, “RNA seeds higher order assembly of FUS protein” Cell Reports, 2013; 5(4):918-25.
4. Schwartz JC, Ebmeier CC, Podell ER, Heimiller J, Taatjes DJ, Cech TR, “FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2” Genes Dev, 2012; 26:2690-95.
5. Schwartz, JC, Younger, S, Nguyen,N, Hardy, D, Monia, BP, Corey, DR, Janowski, BA, “Antisense Transcripts are Targets for Small Activating RNAs”, Nat Struct Mol Biol. 2008 Aug;15(8):842-8.